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Article

Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization.

Cell biochemistry and biophysics - 1 Jan 2009

Patury Srikanth, Geda Prasanthi, Dobry Craig J, Kumar Anuj, Gestwicki Jason E

Abstract excerpt

In eukaryotes, reversible shuttling between the nucleus and cytoplasm is an important regulatory mechanism, particularly for many kinases and transcription factors. Inspired by the natural system, we recently developed a technology to control protein position in budding yeast using a chemical inducer of dimerization (CID). In this method, a nuclear export or localization signal is reversibly appended to a protein...

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PMID: 19159085
DOI: 10.1007/s12013-009-9044-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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