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A new chromogenic assay (HemosIL ThromboPath) is sensitive to major prothrombotic risk factors affecting the protein C pathway. Results of a multicenter study.

Thrombosis research - 1 May 2009

Toulon Pierre, Smirnov Mikhail, Triscott Mark, Safa Omid, Biguzzi Eugenia, Bouziane Kader, Tripodi Armando

Abstract excerpt

The HemosIL ThromboPath assay (Instrumentation Laboratory) is a new chromogenic assay designed to globally evaluate the functionality of the protein C (PC) pathway. It is based on the ability of endogenous APC generated after activation of PC by a snake venom extract (Protac) to reduce the thrombin generation induced by a reagent containing tissue factor. The aim of this multicenter study involving three...

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PMID: 19157524
DOI: 10.1016/j.thromres.2008.11.017

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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