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Article

A modified functional global test to measure protein C, protein S activities and the activated protein C-resistance phenotype.

Thrombosis research - 1 Nov 1998

Gemmati D, Serino M L, Scapoli G L

Abstract excerpt

Identifying a defect affecting the protein C/protein S (PC/PS) anticoagulant system, using a single global test, has recently become possible thanks to a new methodological approach based on the activation of endogenous plasma PC by Protac, derived from Agkistrodon Contortix snake venom (ACV). The introduction of a commercial test (ProC Global), ACV-based, provides a useful tool for the screening of thrombotic...

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Source

Identifiers

PMID: 9806366
DOI: 10.1016/s0049-3848(98)00120-0

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A modified functional global test to measure protein C, protein S activities and the activated protein C-resistance phenotype.PMID 9806366Read ↗

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Screening for abnormalities of the protein C anticoagulant pathway using the ProC Global assay. Results of a European multicenter evaluation.Semantic proximity Read ↗

Screening for risk factors for thrombosis using a new generation of assays developed to evaluate the functionality of the protein C anticoagulant pathway.Semantic proximity Read ↗

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Resistance to activated protein C and low levels of protein S activity in nine thrombophilic families: a correct diagnosis.Semantic proximity Read ↗

Laboratory screening of thrombophilia. Evaluation of the diagnostic efficacy of a global test to detect congenital deficiencies of the protein C anticoagulant pathway.Semantic proximity Read ↗

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