Article
Screening for abnormalities of the protein C anticoagulant pathway using the ProC Global assay. Results of a European multicenter evaluation.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2000
Toulon P, Halbmeyer W M, Hafner G, Schmitt Y, Randgard B, Odpadlik M, Van Den Eynden C, Wagner C
Abstract excerpt
ProC Global is a new global clotting assay designed to evaluate the functionality of the protein C anticoagulant pathway. It is based on the ability of endogenous activated protein C, generated by activation of protein C by Protac, to prolong an activated partial thromboplastin time, and the results are expressed in protein C activation time normalized ratio (PCAT-NR), after normalization. This multicenter trial...
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