Article
Modification of the ProC Global assay using dilution of patient plasma in factor V-depleted plasma as a screening assay for factor V Leiden mutation.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2001
Quincampoix J C, Legarff M, Rittling C, Andiva S, Toulon P
Abstract excerpt
The activated protein C (APC) resistant-factor V (factor V Leiden) has emerged as the most common inherited risk factor for thrombosis in the Caucasian population. Beside DNA analysis, the laboratory diagnosis is often based on the detection of a poor anticoagulant response to exogenous APC. The ProC Global assay (Dade Behring, Marburg, Germany) is a global clotting assay, which was primarily developed to...
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