Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2009

Maier Lisa M, Anderson David E, Severson Christopher A, Baecher-Allan Clare, Healy Brian, Liu David V, Wittrup K Dane, De Jager Philip L, Hafler David A

Abstract excerpt

Multiple sclerosis (MS) is an organ-specific autoimmune disorder that is in part genetically determined. The gene encoding the alpha-chain of the IL-2 receptor, IL2RA, harbors alleles associated with risk to MS and other autoimmune diseases. In addition, IL2RA genetic variants correlate with the levels of a soluble form of the IL-2 receptor in subjects with type 1 diabetes and multiple sclerosis. Here, we show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-2

Share to Interleukin-2 Receptor alpha Subunit

Share to Longitudinal Studies

Share to Multiple Sclerosis

Share to Signal Transduction

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 19155502
DOI: 10.4049/jimmunol.182.3.1541
PMCID: PMC3992946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.PMID 19155502Read ↗

IL2RA Methylation and Gene Expression in Relation to the Multiple Sclerosis-Associated Gene Variant rs2104286 and Soluble IL-2Rα in CD8+ T Cells.Semantic proximity Read ↗

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.Semantic proximity Read ↗

The IL-2 – IL-2 receptor pathway: Key to understanding multiple sclerosisSemantic proximity Read ↗

Biomarkers of systemic inflammation, soluble IL-2Rα and the multiple sclerosis-associated IL2RA SNP rs2104286 in healthy subjects and multiple sclerosis patients.Semantic proximity Read ↗

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.Semantic proximity Read ↗

Multiple sclerosis treatment effects on plasma cytokine receptor levels.Semantic proximity Read ↗

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.Semantic proximity Read ↗

Genetic variants in IL2RA and IL7R affect multiple sclerosis disease risk and progression.Semantic proximity Read ↗

Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.Semantic proximity Read ↗

Association between interleukin 2 receptor A gene polymorphisms (rs2104286 and rs12722489) with susceptibility to Multiple sclerosis in Iranian populationSemantic proximity Read ↗

Variation in the IL7RA and IL2RA genes in German multiple sclerosis patients.Semantic proximity Read ↗

Association of IL2RA and multiple sclerosis risk: A case control, systematic review, and meta-analysis study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.