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Article

Genetic variants in IL2RA and IL7R affect multiple sclerosis disease risk and progression.

Neurogenetics - 1 Aug 2014

Traboulsee Anthony L, Bernales Cecily Q, Ross Jay P, Lee Joshua D, Sadovnick A Dessa, Vilariño-Güell Carles

Abstract excerpt

Multiple sclerosis (MS) is a common demyelinating neurodegenerative disease with a strong genetic component. Previous studies have associated genetic variants in IL2RA and IL7R in the pathophysiology of the disease. In this study, we describe the association between IL2RA (rs2104286) and IL7R (rs6897932) in the Canadian population. Genotyping 1,978 MS patients and 830 controls failed to identify any significant...

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Identifiers

PMID: 24770783
DOI: 10.1007/s10048-014-0403-3
PMCID: PMC5094890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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