Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of IL2RA and multiple sclerosis risk: A case control, systematic review, and meta-analysis study.

Journal of the neurological sciences - 15 May 2025

Rangani Fatemeh, Rakhshi Nahid, Kadkhoda Mezerji Zahra, Alikhah Asieh, Dehghanzad Reyhaneh, Abbasi Babak, Ahmadi Amirhossein, Nikravesh Abbas, Pahlevan Kakhki Majid

Abstract excerpt

The interleukin-2 receptor alpha chain (IL2RA) gene has been implicated in multiple sclerosis (MS) susceptibility, particularly through the rs2104286 and rs12722489 SNPs. However, previous studies have yielded inconsistent results across different populations, likely due to small sample sizes and ethnic variations. This study aimed to investigate the association of IL2RA SNPs with MS risk in eastern Iranian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies
Share to Genetic Association Studies
Share to Genetic Predisposition to Disease
Share to Interleukin-2 Receptor alpha Subunit
Share to Iran
Share to Multiple Sclerosis
Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 40086235
DOI: 10.1016/j.jns.2025.123461

Genes

IL2RA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of IL2RA and multiple sclerosis risk: A case control, systematic review, and meta-analysis study.PMID 40086235Read ↗

Meta-analysis of the association of IL2RA polymorphisms rs2104286 and rs12722489 with multiple sclerosis risk.Semantic proximity Read ↗

Association between interleukin 2 receptor A gene polymorphisms (rs2104286 and rs12722489) with susceptibility to Multiple sclerosis in Iranian populationSemantic proximity Read ↗

Interleukin 2 receptor α gene polymorphism and risk of multiple sclerosis: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.Semantic proximity Read ↗

Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese.Semantic proximity Read ↗

Variants in the IL7RA gene confer susceptibility to multiple sclerosis in Caucasians: evidence based on 9734 cases and 10436 controls.Semantic proximity Read ↗

Association between IL7 Receptor Alpha (Il7ra) gene rs6897932 polymorphism and the risk of Multiple Sclerosis: A meta-regression and meta-analysis.Semantic proximity Read ↗

Interleukin 7 receptor polymorphisms and the risk of multiple sclerosis: A meta-analysis.Semantic proximity Read ↗

Association between interleukin-10 gene polymorphisms and multiple sclerosis susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

Impact of IL-21 Gene Polymorphisms (rs2055979) and the Levels of Serum IL-21 on the Risk of Multiple Sclerosis.Semantic proximity Read ↗

Association of IL4 and IL4R polymorphisms with multiple sclerosis susceptibility in Caucasian population: A meta-analysis.Semantic proximity Read ↗

Meta-analysis of the Selected Genetic Variants in Immune-Related Genes and Multiple Sclerosis Risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.