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The IL-2 – IL-2 receptor pathway: Key to understanding multiple sclerosis

1 Jan 2021

Abstract excerpt

The development, progression, diagnosis and treatment of autoimmune diseases, such as multiple sclerosis (MS), are convoluted processes which remain incompletely understood. Multiple studies demonstrated that the interleukin (IL)-2 - IL-2 receptor (IL-2R) pathway plays a pivotal role within these processes. The most striking functions of the IL-2 - IL-2R pathway are the differential induction of autoimmune...

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PMID: 35005590
DOI: 10.1016/j.jtauto.2021.100123

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