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Article

Structural rearrangements linked to global folding pathways of the Azoarcus group I ribozyme.

Journal of molecular biology - 6 Mar 2009

Chauhan Seema, Behrouzi Reza, Rangan Prashanth, Woodson Sarah A

Abstract excerpt

Stable RNAs must fold into specific three-dimensional structures to be biologically active, yet many RNAs form metastable structures that compete with the native state. Our previous time-resolved footprinting experiments showed that Azoarcus group I ribozyme forms its tertiary structure rapidly (tau < 30 ms) without becoming significantly trapped in kinetic intermediates. Here, we use stopped-flow fluorescence...

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Identifiers

PMID: 19154736
DOI: 10.1016/j.jmb.2008.12.075
PMCID: PMC2651841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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