Article
Dystroglycan and perlecan provide a basal cue required for epithelial polarity during energetic stress.
Developmental cell - 1 Jan 2009
Mirouse Vincent, Christoforou Christina P, Fritsch Cornelia, St Johnston Daniel, Ray Robert P
Abstract excerpt
Dystroglycan localizes to the basal domain of epithelial cells and has been reported to play a role in apical-basal polarity. Here, we show that Dystroglycan null mutant follicle cells have normal apical-basal polarity, but lose the planar polarity of their basal actin stress fibers, a phenotype it shares with Dystrophin mutants. However, unlike Dystrophin mutants, mutants in Dystroglycan or in its extracellular...
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