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Article

Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway.

Cell reports - 24 Mar 2020

Rajakylä Eeva Kaisa, Lehtimäki Jaakko I, Acheva Anna, Schaible Niccole, Lappalainen Pekka, Krishnan Ramaswamy, Tojkander Sari

Abstract excerpt

Defects in the maintenance of intercellular junctions are associated with loss of epithelial barrier function and consequent pathological conditions, including invasive cancers. Epithelial integrity is dependent on actomyosin bundles at adherens junctions, but the origin of these junctional bundles is incompletely understood. Here we show that peripheral actomyosin bundles can be generated from a specific actin...

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PMID: 32209483
DOI: 10.1016/j.celrep.2020.02.096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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