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Article

AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.

Nature cell biology - 1 Jun 2010

Nakano Atsushi, Kato Hisakazu, Watanabe Takashi, Min Kyung-Duk, Yamazaki Satoru, Asano Yoshihiro, Seguchi Osamu, Higo Shuichiro, Shintani Yasunori, Asanuma Hiroshi, Asakura Masanori, Minamino Tetsuo, Kaibuchi Kozo, Mochizuki Naoki, Kitakaze Masafumi, Takashima Seiji

Abstract excerpt

AMP-activated protein kinase (AMPK) is an energy-sensing Ser/Thr protein kinase originally shown to be regulated by AMP. AMPK is activated by various cellular stresses that inhibit ATP production or stimulate ATP consumption. In addition to its role in metabolism, AMPK has recently been reported to reshape cells by regulating cell polarity and division. However, the downstream targets of AMPK that participate in...

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PMID: 20495555
DOI: 10.1038/ncb2060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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