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Article

Interaction of translation initiation factor IF1 with the E. coli ribosomal A site.

Journal of molecular biology - 26 May 2000

Dahlquist K D, Puglisi J D

Abstract excerpt

Initiation Factor 1 (IF1) is required for the initiation of translation in Escherichia coli. However, the precise function of IF1 remains unknown. Current evidence suggests that IF1 is an RNA-binding protein that sits in the A site of the decoding region of 16 S rRNA. IF1 binding to 30 S subunits changes the reactivity of nucleotides in the A site to chemical probes. The N1 position of A1408 is enhanced, while...

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Identifiers

PMID: 10860719
DOI: 10.1006/jmbi.2000.3672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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