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Article

Pervasive hitchhiking at coding and regulatory sites in humans.

PLoS genetics - 1 Jan 2009

Cai James J, Macpherson J Michael, Sella Guy, Petrov Dmitri A

Abstract excerpt

Much effort and interest have focused on assessing the importance of natural selection, particularly positive natural selection, in shaping the human genome. Although scans for positive selection have identified candidate loci that may be associated with positive selection in humans, such scans do not indicate whether adaptation is frequent in general in humans. Studies based on the reasoning of the...

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Share to Polymorphism, Genetic
Share to Recombination, Genetic
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genome, Human

Share to Regulatory Sequences, Nucleic Acid

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Identifiers

PMID: 19148272
DOI: 10.1371/journal.pgen.1000336
PMCID: PMC2613029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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