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Article

Positive natural selection in the human lineage.

Science (New York, N.Y.) - 16 Jun 2006

Sabeti P C, Schaffner S F, Fry B, Lohmueller J, Varilly P, Shamovsky O, Palma A, Mikkelsen T S, Altshuler D, Lander E S

Abstract excerpt

Positive natural selection is the force that drives the increase in prevalence of advantageous traits, and it has played a central role in our development as a species. Until recently, the study of natural selection in humans has largely been restricted to comparing individual candidate genes to theoretical expectations. The advent of genome-wide sequence and polymorphism data brings fundamental new tools to the...

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Identifiers

PMID: 16778047
DOI: 10.1126/science.1124309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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