Article
Constructing genomic maps of positive selection in humans: where do we go from here?
Genome research - 1 May 2009
Akey Joshua M
Abstract excerpt
Identifying targets of positive selection in humans has, until recently, been frustratingly slow, relying on the analysis of individual candidate genes. Genomics, however, has provided the necessary resources to systematically interrogate the entire genome for signatures of natural selection. To date, 21 genome-wide scans for recent or ongoing positive selection have been performed in humans. A key challenge is...
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