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Article

Genome-wide analysis of natural selection on human cis-elements.

PloS one - 10 Sept 2008

Sethupathy Praveen, Giang Hoa, Plotkin Joshua B, Hannenhalli Sridhar

Abstract excerpt

BACKGROUND: It has been speculated that the polymorphisms in the non-coding portion of the human genome underlie much of the phenotypic variability among humans and between humans and other primates. If so, these genomic regions may be undergoing rapid evolutionary change, due in part to natural selection. However, the non-coding region is a heterogeneous mix of functional and non-functional regions. Furthermore,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18781197
DOI: 10.1371/journal.pone.0003137
PMCID: PMC2522239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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