Article
Natural selection at linked sites in humans.
Gene - 30 Oct 2002
Payseur Bret A, Nachman Michael W
Abstract excerpt
Theoretical and empirical work indicates that patterns of neutral polymorphism can be affected by linked, selected mutations. Under background selection, deleterious mutations removed from a population by purifying selection cause a reduction in linked neutral diversity. Under genetic hitchhiking, the rise in frequency and fixation of beneficial mutations also reduces the level of linked neutral polymorphism....
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