Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection of HIV variants with signature genotypic characteristics during heterosexual transmission.

The Journal of infectious diseases - 15 Feb 2009

Sagar Manish, Laeyendecker Oliver, Lee Sandra, Gamiel Jordyn, Wawer Maria J, Gray Ronald H, Serwadda David, Sewankambo Nelson K, Shepherd James C, Toma Jonathan, Huang Wei, Quinn Thomas C

Abstract excerpt

BACKGROUND: Newly infected subjects acquire a limited number of human immunodeficiency virus type 1 (HIV-1) variants with specific genotypic and phenotypic features from the array of viruses present in a chronically infected transmitting partner. METHODS: We examined HIV-1 envelope sequences from the earliest available serum sample after HIV-1 acquisition in 13 newly infected subjects and from their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to env Gene Products, Human Immunodeficiency Virus
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterosexuality

Share to HIV Envelope Protein gp120

Share to Receptors, CCR5

Share to Receptors, CXCR4

Share to Sequence Analysis, Protein

Share to Statistics, Nonparametric

Source

Open in PubMed Open full text

Identifiers

PMID: 19143562
DOI: 10.1086/596557
PMCID: PMC2755256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection of HIV variants with signature genotypic characteristics during heterosexual transmission.PMID 19143562Read ↗

Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10.Semantic proximity Read ↗

Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.Semantic proximity Read ↗

Genetic and antigenic features of the transmitted virus.Semantic proximity Read ↗

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs.Semantic proximity Read ↗

Envelope-Constrained Neutralization-Sensitive HIV-1 After Heterosexual TransmissionSemantic proximity Read ↗

HIV-1 Envelope Glycoprotein Amino Acids Signatures Associated with Clade B Transmitted/Founder and Recent Viruses.Semantic proximity Read ↗

Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner.Semantic proximity Read ↗

Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels.Semantic proximity Read ↗

Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-α Resistance.Semantic proximity Read ↗

Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures.Semantic proximity Read ↗

Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.Semantic proximity Read ↗

Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.