Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner.

PloS one - 1 Jan 2013

Frange Pierre, Meyer Laurence, Jung Matthieu, Goujard Cecile, Zucman David, Abel Sylvie, Hochedez Patrick, Gousset Marine, Gascuel Olivier, Rouzioux Christine, Chaix Marie-Laure

Abstract excerpt

OBJECTIVE: Characterization of HIV-1 sequences in newly infected individuals is important for elucidating the mechanisms of viral sexual transmission. We report the identification of transmitted/founder viruses in eight pairs of HIV-1 sexually-infected patients enrolled at the time of primary infection ("recipients") and their transmitting partners ("donors"). METHODS: Using a single genome-amplification...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV-1
Share to HIV Envelope Protein gp120

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Leukocytes, Mononuclear

Share to RNA, Viral

Share to Sexual Partners

Share to Viral Load

Share to Viral Tropism

Source

Open in PubMed Open full text

Identifiers

PMID: 23874894
DOI: 10.1371/journal.pone.0069144
PMCID: PMC3706485

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner.PMID 23874894Read ↗

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.Semantic proximity Read ↗

Identifying and characterizing recently transmitted virusesSemantic proximity Read ↗

Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-α Resistance.Semantic proximity Read ↗

Genetic and antigenic features of the transmitted virus.Semantic proximity Read ↗

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification.Semantic proximity Read ↗

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.Semantic proximity Read ↗

HIV transmission.Semantic proximity Read ↗

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs.Semantic proximity Read ↗

HIV-1 Transmission during Early Infection in Men Who Have Sex with Men: A Phylodynamic AnalysisSemantic proximity Read ↗

Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 RecipientsSemantic proximity Read ↗

Early-Transmitted Variants and Their Evolution in a HIV-1 Positive Couple: NGS and Phylogenetic Analyses.Semantic proximity Read ↗

Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.