Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Envelope-Constrained Neutralization-Sensitive HIV-1 After Heterosexual Transmission

25 Mar 2004

Abstract excerpt

Heterosexual transmission accounts for the majority of human immunodeficiency virus-1 (HIV-1) infections worldwide, yet the viral properties that determine transmission fitness or outgrowth have not been elucidated. Here we show, for eight heterosexual transmission pairs, that recipient viruses were monophyletic, encoding compact, glycan-restricted envelope glycoproteins. These viruses were also uniquely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15044802
DOI: 10.1126/science.1093137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Envelope-Constrained Neutralization-Sensitive HIV-1 After Heterosexual TransmissionPMID 15044802Read ↗

Selection bias at the heterosexual HIV-1 transmission bottleneckSemantic proximity Read ↗

Identifying and characterizing recently transmitted virusesSemantic proximity Read ↗

Genetic and antigenic features of the transmitted virus.Semantic proximity Read ↗

Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 RecipientsSemantic proximity Read ↗

The evolution of Envelope function during coinfection with phylogenetically distinct Human Immunodeficiency VirusSemantic proximity Read ↗

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs.Semantic proximity Read ↗

Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants.Semantic proximity Read ↗

Broadly neutralizing antibodies developed by an HIV-positive elite neutralizer exact a replication fitness cost on the contemporaneous virus.Semantic proximity Read ↗

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.Semantic proximity Read ↗

Early-Transmitted Variants and Their Evolution in a HIV-1 Positive Couple: NGS and Phylogenetic Analyses.Semantic proximity Read ↗

Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.Semantic proximity Read ↗

Transmitted/Founder and Chronic Subtype C HIV-1 Use CD4 and CCR5 Receptors with Equal Efficiency and Are Not Inhibited by Blocking the Integrin α4β7Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.