Article
Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.
AIDS research and human retroviruses - 1 Jan 2000
Rossenkhan Raabya, MacLeod Iain J, Brumme Zabrina L, Magaret Craig A, Sebunya Theresa K, Musonda Rosemary, Gashe Berhanu A, Edlefsen Paul T, Novitsky Vlad, Essex M
Abstract excerpt
Viral variants that predominate during early infection may exhibit constrained diversity compared with those found during chronic infection and could contain amino acid signature patterns that may enhance transmission, establish productive infection, and influence early events that modulate the infection course. We compared amino acid distributions in 17 patients recently infected with HIV-1C with patients with...
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