Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10.

PloS one - 1 Jan 2020

Lumngwena Evelyn Ngwa, Abrahams Bianca, Shuping Liliwe, Cicala Claudia, Arthos James, Woodman Zenda

Abstract excerpt

Envelope (Env) phenotype(s) that provide transmitted founders (TF) with a selective advantage during HIV-1 transmission would be the ideal target for preventative therapy. We generated Env clones from four individuals infected with a single virus and one participant infected with multiple variants at transmission and compared phenotype with matched Envs from chronic infection (CI). When we determined whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to env Gene Products, Human Immunodeficiency Virus

Share to Glycosylation

Share to Interleukin-10

Share to Lectins, C-Type

Share to Vaccines, DNA

Share to Virus Internalization

Source

Open in PubMed Open full text

Identifiers

PMID: 31978062
DOI: 10.1371/journal.pone.0227533
PMCID: PMC6980567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10.PMID 31978062Read ↗

Phenotypic properties of transmitted founder HIV-1.Semantic proximity Read ↗

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.Semantic proximity Read ↗

Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences.Semantic proximity Read ↗

Phenotypic and Immunologic Comparison of Clade B Transmitted/Founder and Chronic HIV-1 Envelope GlycoproteinsSemantic proximity Read ↗

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs.Semantic proximity Read ↗

Selection of HIV variants with signature genotypic characteristics during heterosexual transmission.Semantic proximity Read ↗

Genetic and antigenic features of the transmitted virus.Semantic proximity Read ↗

Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.Semantic proximity Read ↗

Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.Semantic proximity Read ↗

Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 RecipientsSemantic proximity Read ↗

HIV-1 replicates and persists in vaginal epithelial dendritic cellsSemantic proximity Read ↗

Variants from the diverse virus population identified at seroconversion of a clade A human immunodeficiency virus type 1-infected woman have distinct biological properties.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.