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Article

Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures.

Retrovirology - 26 Jan 2017

Nakamura Kyle J, Heath Laura, Sobrera Edwin R, Wilkinson Thomas A, Semrau Katherine, Kankasa Chipepo, Tobin Nicole H, Webb Nicholas E, Lee Benhur, Thea Donald M, Kuhn Louise, Mullins James I, Aldrovandi Grace M

Abstract excerpt

BACKGROUND: Mother-to-child transmission of human immunodeficiency virus-type 1 (HIV-1) poses a serious health threat in developing countries, and adequate interventions are as yet unrealized. HIV-1 infection is frequently initiated by a single founder viral variant, but the factors that influence particular variant selection are poorly understood. RESULTS: Our analysis of 647 full-length HIV-1 subtype C and G...

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Share to Breast Feeding
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Infectious Disease Transmission, Vertical

Share to Maternal-Fetal Exchange

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Source

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Identifiers

PMID: 28122636
DOI: 10.1186/s12977-017-0331-z
PMCID: PMC5267468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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