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Article

Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.

Virology - 20 Jan 2010

Treurnicht F K, Seoighe C, Martin D P, Wood N, Abrahams M-R, Rosa D de Assis, Bredell H, Woodman Z, Hide W, Mlisana K, Karim S Abdool, Gray C M, Williamson C

Abstract excerpt

It is unresolved whether recently transmitted human immunodeficiency viruses (HIV) have genetic features that specifically favour their transmissibility. To identify potential "transmission signatures", we compared 20 full-length HIV-1 subtype C genomes from primary infections, with 66 sampled from ethnically and geographically matched individuals with chronic infections. Controlling for recombination and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19913270
DOI: 10.1016/j.virol.2009.10.002
PMCID: PMC2810538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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