Article
HIV-1 Envelope Glycoprotein Amino Acids Signatures Associated with Clade B Transmitted/Founder and Recent Viruses.
Viruses - 1 Nov 2019
Kafando Alexis, Martineau Christine, El-Far Mohamed, Fournier Eric, Doualla-Bell Florence, Serhir Bouchra, Kazienga Adama, Sangaré Mohamed Ndongo, Sylla Mohamed, Chamberland Annie, Charest Hugues, Tremblay Cécile L
Abstract excerpt
BACKGROUND: HIV-1 transmitted/founder viruses (TF) are selected during the acute phase of infection from a multitude of virions present during transmission. They possess the capacity to establish infection and viral dissemination in a new host. Deciphering the discrete genetic determinant of infectivity in their envelope may provide clues for vaccine design. METHODS: One hundred twenty-six clade B HIV-1 consensus...
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