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Article

Association of alleles at polymorphic sites in the Osteopontin encoding gene in young type 1 diabetic patients.

Clinical immunology (Orlando, Fla.) - 1 Apr 2009

Marciano Renato, D'Annunzio Giuseppe, Minuto Nicola, Pasquali Lorenzo, Santamaria Andrea, Di Duca Marco, Ravazzolo Roberto, Lorini Renata

Abstract excerpt

The Osteopontin (OPN) encoding gene, SPP1, can be considered as a candidate for genetic susceptibility to type 1 diabetes (T1D) because of its known function in immune response and inflammation. This work aimed to evaluate the role of SPP1 gene in susceptibility to T1D. Patients (238: 130 male, 108 female) and unaffected adult control individuals (137: 68 males and 69 females) have been genotyped for three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19138884
DOI: 10.1016/j.clim.2008.11.004

Genes

SPP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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