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Article

Association of SPP1 promoter variants with hip osteoarthritis susceptibility in Chinese population.

Gene - 10 Jun 2015

Lv Chuanjian, Li Yan, Xu Junling, Cao Huichun, Li Xiaoxiao, Ma Bo, Ning Peigang, Wang Yan, Wang Meiyun, Zhu Shaocheng, Ge Yinghui, Huang Suizhu, Jin Yi

Abstract excerpt

Three genetic variants in the promoter of SPP1 (secreted phosphoprotein 1) gene have been reported to affect transcriptional activity of SPP1, thus conferring an increased risk for some diseases. To testify if these variants are associated with risk of hip osteoarthritis (OA) as well, we performed a case-control study including 389 hip OA patients and 315 healthy controls. Genotypes of SPP1 were determined by DNA...

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Source

Identifiers

PMID: 25796600
DOI: 10.1016/j.gene.2015.03.036

Genes

SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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