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Article

Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes.

International journal of immunogenetics - 1 Dec 2007

Nielsen C, Hansen D, Husby S, Lillevang S T

Abstract excerpt

Type 1 diabetes (T1D) is a common organ-specific autoimmune disease of complex aetiology, involving the interaction of a large number of disease-associated genes. By comparison of a Danish population sample of 253 Caucasian children and adolescents with T1D and a control group consisted of 354 unrelated healthy blood donors, the present study provides evidence of an isolated association of the disease-associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18001305
DOI: 10.1111/j.1744-313X.2007.00720.x

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes.PMID 18001305Read ↗

Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto’s thyroiditis or Addison’s disease in the German populationSemantic proximity Read ↗

The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population.Semantic proximity Read ↗

Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.Semantic proximity Read ↗

C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?Semantic proximity Read ↗

PTPN22 R620W functional variant in type 1 diabetes and autoimmunity related traits.Semantic proximity Read ↗

Association between the 1858T allele of the protein tyrosine phosphatase nonreceptor type 22 and type 1 diabetes in a Brazilian population.Semantic proximity Read ↗

PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Semantic proximity Read ↗

Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population.Semantic proximity Read ↗

The putative role of the C1858T polymorphism of protein tyrosine phosphatase PTPN22 gene in autoimmunity.Semantic proximity Read ↗

Role of the C1858T polymorphism of protein tyrosine phosphatase non-receptor type 22 (PTPN22) in children and adolescents with type 1 diabetes.Semantic proximity Read ↗

Type 1 diabetes mellitus. Comparison between the association with PTPN22 genotype and the association with ACP1-ADA1 joint genotype.Semantic proximity Read ↗

PTPN22 1858T allele is associated with younger age at onset of type 1 diabetes and is not related to subsequent thyroid autoimmunity.Semantic proximity Read ↗

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