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Article

Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1Δ Mutation.

Journal of microbiology and biotechnology - 28 Mar 2017

Lee Ji Young, Jun Do Youn, Park Ju Eun, Kwon Gi Hyun, Kim Jong-Sik, Kim Young Ho

Abstract excerpt

To examine the pro-apoptotic role of the human ortholog (YPEL5) of the Drosophila Yippee protein, the cell viability of Saccharomyces cerevisiae mutant strain with deleted MOH1, the yeast ortholog, was compared with that of the wild-type (WT)-MOH1 strain after exposure to different apoptogenic stimulants, including UV irradiation, methyl methanesulfonate (MMS), camptothecin (CPT), heat shock, and hyperosmotic...

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Source

Identifiers

PMID: 28173693
DOI: 10.4014/jmb.1610.10045

Genes

YPEL5
YPEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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