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Article

Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study.

Stroke - 1 Mar 2009

Bevan Steve, Lorenz Matthias W, Sitzer Matthias, Markus Hugh S

Abstract excerpt

BACKGROUND AND PURPOSE: The recent finding that genetic variation in the leukotriene biosynthesis pathway may confer an increased risk of ischemic stroke and atherosclerosis has implicated the leukotriene family as potential mediators of cardiovascular disease. Using a 2-stage replication design, we have examined whether polymorphisms in 8 genes related to this pathway are associated with early atherosclerosis...

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PMID: 19131661
DOI: 10.1161/STROKEAHA.108.525733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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