Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll receptor polymorphisms and carotid artery intima-media thickness.

Stroke - 1 Apr 2007

Labrum Robyn, Bevan Steve, Sitzer Matthias, Lorenz Matthias, Markus Hugh S

Abstract excerpt

BACKGROUND AND PURPOSE: Inflammation is a key mechanism in atherosclerosis. Variation in genes encoding inflammatory responses may therefore influence atherosclerosis risk possibly through interaction with chronic infections and proinflammatory environmental risk factors such as smoking, diabetes, and obesity. The Toll-like receptor family (TLRs) genes TLR2 and TLR4, both involved in the inflammatory process, are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Arteries
Share to Carotid Artery Diseases
Share to Diabetes Complications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Toll-Like Receptor 2

Share to Toll-Like Receptor 4

Share to Toll-Like Receptors

Share to Tunica Intima

Share to Tunica Media

Source

Identifiers

PMID: 17332447
DOI: 10.1161/01.STR.0000260184.85257.2b

Genes

TLR4
TLR2
CAPS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll receptor polymorphisms and carotid artery intima-media thickness.PMID 17332447Read ↗

Effect of the Toll-like receptor 4 (TLR-4) variants on intima-media thickness and monocyte-derived macrophage response to LPS.Semantic proximity Read ↗

The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.Semantic proximity Read ↗

Toll-like Receptors and Atherosclerosis: Key Contributors in Disease and Health?Semantic proximity Read ↗

Inflammation and endothelial function-related gene polymorphisms are associated with carotid atherosclerosis-A study of community population in Southwest China.Semantic proximity Read ↗

Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.Semantic proximity Read ↗

Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.Semantic proximity Read ↗

Angiotensinogen and angiotensin converting enzyme genotypes and carotid atherosclerosis: the atherosclerosis risk in communities and the NHLBI family heart studies.Semantic proximity Read ↗

Genetic and acquired inflammatory conditions are synergistically associated with early carotid atherosclerosis.Semantic proximity Read ↗

Frequency of TLR 2, 4, and 9 gene polymorphisms in Chinese population and their susceptibility to type 2 diabetes and coronary artery disease.Semantic proximity Read ↗

Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study.Semantic proximity Read ↗

Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.