Article
Genetic association studies in stroke: methodological issues and proposed standard criteria.
Stroke - 1 Sept 2005
Dichgans Martin, Markus Hugh S
Abstract excerpt
BACKGROUND AND PURPOSE: A large number of candidate gene association studies have attempted to identify genes implicated in stroke, but there have been few replicable and robust associations reported. SUMMARY OF REVIEW: The skantness of replicable associations partly relates to poor study design. Important methodological considerations include adequate sample size, the selection of appropriate controls, careful...
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