Article
No association of nineteen COX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study.
BMC medical genetics - 2 Jul 2012
Lähteelä Kati, Kunnas Tarja, Lyytikäinen Leo-Pekka, Mononen Nina, Taittonen Leena, Laitinen Tomi, Kettunen Johannes, Juonala Markus, Hutri-Kähönen Nina, Kähönen Mika, Viikari Jorma S, Raitakari Olli T, Lehtimäki Terho, Nikkari Seppo T
Abstract excerpt
BACKGROUND: The role of cyclooxygenase-2 (COX-2) single nucleotide polymorphisms has mostly been studied in relation to advanced atherosclerosis, but little is known how they contribute to preclinical disease. In the present study we analyzed whether COX-2 gene variants associate independently wi...
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