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Article

Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study.

Atherosclerosis - 1 Jun 2015

Dong Chuanhui, Della-Morte David, Beecham Ashley, Wang Liyong, Cabral Digna, Blanton Susan H, Sacco Ralph L, Rundek Tatjana

Abstract excerpt

BACKGROUND: There is an established sex-difference in carotid artery intima-media thickness (cIMT), a recognized marker of subclinical atherosclerosis. However, the genetic underpinnings of sex-differences in gene-IMT associations are largely unknown. METHODS: With a multistage design using 731,037 single nucleotide polymorphisms (SNP), a genome wide interaction study was performed in a discovery sample of 931...

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Source

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Identifiers

PMID: 25898001
DOI: 10.1016/j.atherosclerosis.2015.04.019
PMCID: PMC4441583

Genes

GALNT10
LEKR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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