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Article

Meat consumption, heterocyclic amines, NAT2, and the risk of breast cancer.

Nutrition and cancer - 1 Jan 2009

Mignone Laura I, Giovannucci Edward, Newcomb Polly A, Titus-Ernstoff Linda, Trentham-Dietz Amy, Hampton John M, Orav E John, Willett Walter C, Egan Kathleen M

Abstract excerpt

Meat consumption and heterocyclic amine (HCA) intake have been inconsistently associated with breast cancer risk in epidemiologic studies. Genetic variation in N-acetyltransferase2 (NAT2) has been suggested to modify the association of meat intake with breast cancer through its influence on metabolism of HCAs. We examined associations between meat intake, HCA exposure, acetylator genotype, and breast cancer risk...

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Source

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Identifiers

PMID: 19116874
DOI: 10.1080/01635580802348658
PMCID: PMC4902008

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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