A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer.

doi:10.1093/aje/kwm066

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Article

A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer.

American journal of epidemiology - 1 Aug 2007

Ochs-Balcom Heather M, Wiesner Georgia, Elston Robert C

Abstract excerpt

The N-acetyltransferase 2 gene (NAT2) product is an enzyme important in carcinogen metabolism via activation and detoxification pathways. Therefore, NAT2 variants may represent underlying susceptibility to breast cancer. Because a number of studies of the association of NAT2 with breast cancer have been published, the authors performed a meta-analysis. They extracted all relevant data to examine evidence for a...

Topics

Arylamine N-Acetyltransferase
Breast Neoplasms
Female
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Odds Ratio
Phenotype
Smoking

Source

Open in PubMed

Identifiers

PMID: 17535831
DOI: 10.1093/aje/kwm066

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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