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Article

Fine mapping versus replication in whole-genome association studies.

American journal of human genetics - 1 Nov 2007

Clarke Geraldine M, Carter Kim W, Palmer Lyle J, Morris Andrew P, Cardon Lon R

Abstract excerpt

Association replication studies have a poor track record and, even when successful, often claim association with different markers, alleles, and phenotypes than those reported in the primary study. It is unknown whether these outcomes reflect genuine associations or false-positive results. A greater understanding of these observations is essential for genomewide association (GWA) studies, since they have the...

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Identifiers

PMID: 17924341
DOI: 10.1086/521952
PMCID: PMC2265650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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