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Article

Interleukin-18 gene promoter polymorphisms in women with gestational trophoblastic diseases.

The Journal of reproductive medicine - 1 Nov 2008

Kashef Mohammad Amin, Dehaghani Alamtaj Samsami, Naeimi Sirous, Fattahi Mohammad Javad, Ghaderi Abbas

Abstract excerpt

OBJECTIVE: Gestational trophoblastic diseases (GTDs) consist of a spectrum of disorders characterized by an abnormal proliferation of trophoblastic tissue. IL-18 is a pleiotropic cytokine with a capacity for both ThI and Th2 polarization. Considering the association of IL-18 promoter polymorphisms at positions -607 (A/C) and -137 (C/G) with pregnancy events and some cancers, we sought to examine these...

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PMID: 19097518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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