Article
Investigating the Association of IL-17A and IL-17F with Susceptibility to Pre-eclampsia in Iranian Women.
Iranian journal of immunology : IJI - 1 Jun 2015
Anvari Fahimah, Dabagh-Gorjani Feryal, Soltani-Zangbar Mohammad-Sadegh, Kamali-Sarvestani Eskandar, Malek-Hosseini Zahra, Gharesi-Fard Behrouz
Abstract excerpt
BACKGROUND: Pre-eclampsia (PE) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. Imbalance in helper T cell functions may play a role in predisposing to PE or severity of the disease. Elevated frequencies of Th17 cells in the peripheral blood of PE patients have been reported. Several single nucleotide polymorphisms (SNP) within IL-17 gene have...
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