Article
Investigating the Association of IL-17A and IL-17F with Susceptibility to Pre-eclampsia in Iranian Women.
Iranian journal of immunology : IJI - 1 Jun 2015
Anvari Fahimah, Dabagh-Gorjani Feryal, Soltani-Zangbar Mohammad-Sadegh, Kamali-Sarvestani Eskandar, Malek-Hosseini Zahra, Gharesi-Fard Behrouz
Abstract excerpt
BACKGROUND: Pre-eclampsia (PE) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. Imbalance in helper T cell functions may play a role in predisposing to PE or severity of the disease. Elevated frequencies of Th17 cells in the perip...
Topics
- Adult
- Case-Control Studies
- Female
- Fetal Blood
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-17
- Iran
- Lymphocyte Count
- Placenta
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide
- Pre-Eclampsia
- Pregnancy
- RNA, Messenger
- Th17 Cells