Article
Association study of IL-10 and IFN-gamma gene polymorphisms in Iranian women with preeclampsia.
Journal of reproductive immunology - 1 Dec 2006
Kamali-Sarvestani Eskandar, Kiany Simin, Gharesi-Fard Behrouz, Robati Minoo
Abstract excerpt
Preeclampsia (PE) is one of the most serious disorders of human pregnancy and Th1/Th2 imbalance may play a role in its etiology. Considering that cytokine production is under genetic control, in this study we have investigated IFN-gamma+874 (T/A) and three bi-allelic IL-10 promoter polymorphisms in a total of 134 preeclamptic women compared to 164 healthy women. It was shown that the IL-10 -1082 G allele...
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