Article
Genetic variant in interleukin-18 is associated with idiopathic recurrent miscarriage in Chinese Han population.
International journal of molecular sciences - 16 Feb 2015
Yue Jun, Tong Yu, Zhou Jing, Liu Qingqing, Yang Jiyun
Abstract excerpt
Levels of IL-18 were significantly lower in women with recurrent miscarriage (RM) than those without idiopathic RM. IL-18 promoter single nucleotide polymorphisms were previously identified to have an impact on IL18 gene transcription activity and influence the level of IL-18 protein production. The aim of this study was to evaluate whether IL-18 gene polymorphisms are risk factors for idiopathic RM in Chinese...
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