Article
Interleukin 10 gene promoter polymorphisms in women with early-onset pre-eclampsia.
Clinical and experimental immunology - 1 Nov 2014
Sowmya S, Sri Manjari K, Ramaiah A, Sunitha T, Nallari P, Jyothy A, Venkateshwari A
Abstract excerpt
Pre-eclampsia is one of the most serious disorders of human pregnancy and T helper type 1 (Th1)/Th2 imbalance plays a major role in its aetiology. The Th2 cytokine, interleukin (IL)-10, plays a significant role in the maintenance of pregnancy. The present study is aimed at understanding the role of IL-10 promoter polymorphisms (-1082 G/A; -592 A/C and -819 C/T) and their haplotypes in early-onset pre-eclampsia. A...
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