Article
A functional polymorphism in the promoter region of interleukin-10 gene increases the risk for spontaneous abortions--a triad study.
Journal of assisted reproduction and genetics - 1 Jul 2015
Vidyadhari M, Sujatha M, Krupa P, Jyothy A, Nallari Pratibha, Venkateshwari A
Abstract excerpt
PURPOSE: Spontaneous abortion or miscarriage is the natural death of an embryo or foetus in the early stages of prenatal development. Interleukin-10 is an anti-inflammatory cytokine, produced by human cytotrophoblasts, and defects in its production result in specific pathological conditions during pregnancy. The present study is aimed to evaluate the association of IL-10 -1082G/A polymorphism in spontaneous...
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