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Article

Polymorphisms in the interleukin-12/18 genes and recurrent spontaneous abortion.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2007

Ostojić Sasa, Volk Marija, Medica Igor, Kapović Miljenko, Meden-Vrtovec Helena, Peterlin Borut

Abstract excerpt

PROBLEM: Interleukin (IL) IL-12/IL-18 are involved in uterine NK cells control of uterine vascular development. Polymorphisms in the IL-12/IL-18 genes could modify the cytokine balance, which might result in an increased susceptibility to recurrent spontaneous abortion (RSA). METHOD OF STUDY: A case-control study was conducted to determine the association between the IL12 (I/D) and IL18 (-607C>A, -137G>C) gene...

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Source

Identifiers

PMID: 17922692
DOI: 10.1111/j.1600-0897.2007.00501.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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