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Article

PDCD1, CTLA-4 and p53 gene polymorphism and susceptibility to gestational trophoblastic diseases.

The Journal of reproductive medicine - 1 Jan 2009

Dehaghani Alamtaj Samsami, Kashef Mohammad Amin, Ghaemenia Mehdi, Sarraf Zahra, Khaghanzadeh Narges, Fattahi Mohammad Javad, Ghaderi Abbas

Abstract excerpt

OBJECTIVE: Gestational trophoblastic neoplasms (also termed gestational trophoblastic diseases [GTDs]) encompass a spectrum of interrelated tumors originating from trophoblasts. The search is ongoing for identification of the culpable gene defects in GTDs. Considering the role of PDCD1, CTLA-4 and p53 genes in immune regulation and tumor progression, we explored the association of single-nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19263877

Genes

PDCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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