Article
Significant evidence for linkage to chromosome 5q13 in a genome-wide scan for asthma in an extended pedigree resource.
European journal of human genetics : EJHG - 1 May 2009
Teerlink Craig C, Camp Nicola J, Bansal Aruna, Crapo Robert, Hughes Dana, Kort Edward, Rowe Kerry, Cannon-Albright Lisa A
Abstract excerpt
Asthma is a multifactorial disease with undetermined genetic factors. We performed a genome-wide scan to identify predisposition loci for asthma. The asthma phenotype consisted of physician-confirmed presence or absence of asthma symptoms. We analyzed 81 extended Utah pedigrees ranging from three to six generations, including 742 affected individuals, ranging from 2 to 40 per pedigree. We performed parametric...
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