Article
A large-scale, consortium-based genomewide association study of asthma.
The New England journal of medicine - 23 Sept 2010
Moffatt Miriam F, Gut Ivo G, Demenais Florence, Strachan David P, Bouzigon Emmanuelle, Heath Simon, von Mutius Erika, Farrall Martin, Lathrop Mark, Cookson William O C M
Abstract excerpt
BACKGROUND: Susceptibility to asthma is influenced by genes and environment; implicated genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in identifying subtypes of asthma and determining whether intermediate phenotypes, such as elevation of the total serum IgE level, are causally linked to disease. METHODS: We carried out a genomewide association study by genotyping...
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