Article
Genome-wide approaches for identifying interacting susceptibility regions for asthma.
Genetic epidemiology - 1 Jan 2001
Colilla S, Tsalenko A, Pluznikov A, Cox N J
Abstract excerpt
A genome-wide correlation analysis and cluster analysis were utilized to determine chromosomal regions that had similar nonparametric linkage scores across families in order to locate interacting susceptibility loci for asthma. Conditional analysis was performed to detect any increase in lod score over baseline. Eight of the strongest 5% of the correlations in the German and CSGA asthma data sets occurred in both...
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